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If a dog requires an intricate trim, has matting, an adverse temperament, or substantial amounts of coat the time required can increase considerably. The poor dog is on so many medications right now.
The first week of radiation therapy was mostly uneventful. The only side effects we found were her being lethargic normal for her after anesthesia and a reduced appetite. We felt that her appetite was reduced more due to discomfort and just not feeling good after anesthesia more than anything.
We started cooking beef, chicken and broccoli for her and she seems happy. The improvement in breathing came after treatment day 3; which was really unexpected. I am not sure if they were zapping the right places or the swelling in her nose was going down but she really looks and sounds a lot better.
It does beat the cone type anti scratch collar though. The port is huge under her skin. She can no longer wear a standard collar with it so we looked for a harness for her.
No loss of hair and appetite back to normal. We had a great three day weekend with her and it felt like all was normal. There was more sneezing this week, and it got pretty gross.
The vet had warned us that she would start to cough and sneeze out some of the tumor and mucus that was in her nose. She sure did, and it got everywhere. We recommend putting down old sheets or towels on your furniture, in your car, or wherever else the dog normally goes. As strange as it sounds, the gross coming out almost felt like a victory and that we were winning in some kind of disgusting way.
The burns just appeared out of nowhere. I thought it would be a gradual thing where she lost the hair first then get a sunburn then blisters. Nope… it went straight to horrible red and yellow blisters below both eyes. We are trying to stick to her medication schedule as closely as possible but you can tell she is in pain.
She is shaking and just sitting and staring at random walls. She is being really great about us sticking our fingers in her oozing burns and waits at least 5 minutes before sneaking off and rubbing it off. She is having a problem eating dry food again. We assume this is because she has similar burns in her mouth.
We switched her to canned science diet and that seemed to do the trick. Emotionally this period has been the roughest, as seeing the visible damages from the radiation treatment on your dog is hard to take. We still feel that we are doing the right thing and are hoping that the final outcome will be a much increased lifespan and good quality of life.
It is just hard knowing you are putting your pet through pain and not being able to explain to them why you are doing so. The radiation burns have gotten much worse. Hair has completely fallen out in two large areas.
We are still putting on the creams religiously to help soothe the skin.Highly coveted horses from other strains were occasionally interbred if the intertribal conditions were right and the stallion esteemed by the owner of the war mares. The ears were cut off the young working dogs so that all that remained were blunt stubs that could not be torn during a fight. Induced Estrus It appears that in some cases, the presence of a female in heat may awaken the heat cycle as well in other females. Signs include abnormal bone remodeling, lameness, and death.
After a few days of doing this the skin still looked bad, so they also prescribed an antibiotic to take as well. The poor dog is on so many medications right now.
Some new behaviors have started as well. Nunya has been housebroken for well over a decade and has not had an accident inside in many years.
One time she peed in the car on the way to the vet office. The next day she peed in our house. We are not sure if she did this because her schedule is off with the early morning vet visits and that threw her, or if it is medication related and holding her bladder is harder, or if she is doing this out of nerves she hates going to the vet or spite.
She is still in pain too. Once she gets home she will just sit around and stare at nothing. Her appetite is also reduced again.How To Understand Your Dog's Heat Cycle
She will lick at the liquid in her dog food but just picks at the solid parts. Mostly she just lays around and sleeps.
We are very much looking forward to the last day of radiation treatment. The tomotherapy is now complete! The consult with the Dr was overall positive with a lot of warnings.
The radiation will continue to shrink the tumor for the next week hopefully. The downside to that, is the acute side effects can begin after treatment stops.
Poor Nunya is already sore. They suggested leaving the port in her neck forever, which means she cannot wear here NunStrong collar. We go back in 2 weeks to do a quick check up no ct scan yet.
Exact notes from the Doctor: Congratulations to you and Nunya for completing her TomoTherapy! As we discussed previously, acute side effects after radiation can begin soon after treatment, and may last for several weeks after treatment is completed.
You may see hair loss, change in skin and hair color in that area, or ulceration of the skin. Continue to apply the creams and give the antibiotic to prevent infection. Indication of infection would be green, white, or yellow discharge from underneath her eyes.
Nunya may appear sensitive or painful around her left eye, nose, and mouth.How Long Is A Dog In Heat Bleed?
Some longer term effects might include the slight possibility that the mineral in the bone in the area can be replaced by fibrous tissue and become soft and predisposed to fractures.
Nunya will also always be predisposed to rhinitis infection of the nasal tissues for the rest of her life, since the tissue in her nose will never be completely normal anatomically again after the tumor destruction and the radiation effects—so she may need intermittent antibiotic treatment.
Nunya is a very sweet dog and a wonderful patient! Thank you so much for entrusting Nunya in our care! The burned area on her face has continued to grow as expected.
Nunya has tried to scratch at her face but we are doing our best to keep that down. It is a little more crusty than before — not sure if this is a negative or a positive.
We did have an amazing weekend with her. Most of the scabs are gone and the flesh looks a lot less red. Her appetite is back and she has finished her antibiotic.
The one negative during this period — she seems to be more congested and sneezing a lot more. So far, the sneezes have not contained any blood. We are looking forward to her check up on Monday.
The vet said she looked good and overall gave a good report. Our main concern had been her constant sneezing and hyperventilating. These were symptoms that started just before the cancer diagnosis. She said it was most likely due to post-nasal drip, which is an effect of the radiation.
We should monitor Nunya and if the symptoms majorly worsen, or if she starts bleeding from the nose or mouth, we should let them know. Otherwise she should be fine. That answer will come in about two months at her next check-up, when they will do another scan on her. The next step will be to start chemotherapy on her.
This will consist of a daily pill regimen that will include the chemo pill Cyclophosphamidea diuretic pill Furosemideand an anti-inflammation medication.
The chemo treatment is something that Nunya will likely be on long-term. The vet said most dogs who go on it will be on it for about a year to forever. That was not fun to hear, but if it increases her lifespan and helps prevent the cancer from coming back we are game. There are no guarantees of how effective her treatment will be in the long term, but it is the best chance for her so we will do it.
The chemo pills need special handling and require gloves to administer. I am pretty sure Nunya will love that. Update later in the day — We were called by the vet later on in the afternoon to go over a blood test finding from earlier in the day.
The vet did not have an explanation for why this occurred, so wants to do an ultrasound to see what might be going on. The chemotherapy treatments will be delayed until this new problem is sorted out first. We are waiting a week and then bringing her to the local vet for another round of blood tests.
Nunya handled the ultrasound like a champ. She was a little groggy afterward but was active and hungry by 5pm. Nunya had her second blood test done on Wednesday and we got the results today. Liver functions are looking a lot better but still not where they need to be.
It was recommended that we delay chemo and have her tested again in two weeks. Overall, she seems to be doing well. Sneezing a lot still but no blood and less snot. We did have two positive events happen this week: While this marker was always an estimate, it was an important marker for us in evaluating if we did the right thing with her tomotherapy treatments.
She smelled the cable man. Seems silly but small victories still count. Internet was being flaky and Comcast had to come out to test the line. Nunya was closed off in my office with me while the guy was working. To my surprise, she lifted her head and started audibly sniffing and immediately knew someone was in the house got the full bark alert.
There really has not been much change in the last week. She has lost more hair around her nose and a spot on her head. We have not seen her scratching so we are not really sure why we still see the increase in hair loss. Next week is the follow up blood test.
She is still on the liver medication, taking both Ursodial and Denosyl to help improve her liver functions. We also put Aquaphor cream on her exposed skin patches to help heal the dry skin.We have another blood test scheduled this week to see if the chemotherapy medication is bothering her liver. Basically a female dog will exhibit signs of pro-estrus with the typical bleeding but then once estrus approaches the symptoms disappear for some time.
Nunya had to have another blood test last week to check her liver levels again. The results came back showing more improvement, and her levels are close to normal. The oncologist said that she can start on her chemotherapy medications now.
The meds were ordered and should arrive in about days. She will then need to have her blood re-tested in about two weeks, and a follow up visit with the oncologist in six weeks. Nunya has been doing well otherwise and seems to feel good.
Some hair is growing back sporadically in her radiation burn patches as well. She has been doing well. She has been feeling up to daily walks around the neighborhood. We are still waiting on one of the chemo drugs, but we anticipate her starting the combination of pills this week.
Her bald spots are filling in quickly with golden blonde hair even in the places that were white hair before. The doctors told us that it was a possibility that if the hair came back it would be different. Nunya had her first chemotherapy medication today.
She takes Cyclophosphamide and Furosemide once daily. The directions say to give it in the morning as it will cause frequent urination. Nunya lets herself outside through a doggy door, so hopefully that will not be an issue for her.
The Cyclophosphamide directions say to wear gloves when handling the medication. Kind of an unnerving warning. Nunya took both meds like a champ, however seemed to have a hard time getting the Cyclophosphamide down.
Almost a week after the first dose and all seems to be going welling. Urination has increased and sleeping a little bit more. Hard to tell if it is the cold outside and the warm bed sucking her in and not the medicine I am guilty of spending a lot of time in bed with her this weekend.
Nothing major to report. We have another blood test scheduled this week to see if the chemotherapy medication is bothering her liver.
Liver functions are still looking improved. Nunya is to stay on all current meds and her next appointment will be the big CT scan on Feb 12th. Today has been filled with treats and Ringos.
Promotes the body's absorption of calcium, which is essential for normal development and maintenance of healthy teeth and bones. It also helps maintain adequate blood levels of calcium and phosphorus. Can be manufactured by the body under sufficient exposure to UV radiation.
Ten to 15 minutes of sunshine 3 times weekly is adequate to produce the body's requirement of vitamin D. Signs of deficiency include bone malformations rickets characterized by bowing of the legs, thickening of the joints, and an increased incidence of fractures.
Excessive vitamin D supplementation can result in increased calcium absorption from the intestines. This can cause increased calcium resorption from the bones, leading to elevated levels of calcium in the blood. Elevated blood calcium may contribute to calcium deposition in soft tissues such as the heart and lungs.
This can reduce their ability to function. Stable in food storage, cooking and processing. Vitamin D is only found naturally in animals and animal products.
Halibut and cod liver oil, saltwater fish, cheese, yogurt, eggs. Vitamin E Tocopherol Effects: Acts as a biological antioxidant, and is required for normal reproduction.
There are several forms of vitamin E. The most biologically active form is know as alpha-tocopherol, which should be supplemented as alpha-tocopherol, alpha-tocopherol acetate, or alpha-tocopherol succinate. Other forms, like gamma-tocopherol or beta-tocopherol, do not provide the same level of protection.
Vitamin E from natural sources is labeled as alpha tocopherol or d-alpha tocopherol - dl-alpha tocopherol indicates a synthetic, less effective product. Do not give cheap vitamin E supplements that contain high levels of vitamin A, since this could lead to an overdose of vitamin A and possibly vitamin A toxicity.
Vitamin E is also important for the formation of red blood cells and it helps the body to utilize vitamin K. A deficiency of vitamin E can lead to decreased reproductive performance, retinal degeneration, and impairment of the immune system.
None known, but high levels of vitamin E can adversely affect the absorption of vitamins A and K, causing deficiencies. In the case of vitamin K this can interfere with normal blood clotting. Vitamin E is sensitive to heat, light and oxygen and significant losses have been found after relatively short times of food storage.
Wheat germ, corn, nuts, seeds, spinach and other green leafy vegetables, asparagus, vegetable oils. Vitamin K Naphthoquinone Effects: Required for blood clotting.
The bacteria present in the healthy intestine can synthesize all the vitamin K the body needs, so supplementation is generally not necessary. Very rare, but occurs when there is an inability to absorb fats or the vitamin from the intestinal tract. Can also occur after prolonged treatment with oral antibiotics.
Increased tendency to bruise and bleed. Relatively stable to heat, but sensitive to acid, alkali, light and oxidizing agents. Cabbage, cauliflower, spinach and other green leafy vegetables, cereals, soybeans, and other vegetables.
Also producecd by the bacteria in the healthy gastrointestinal tract. Water soluble vitamins Vitamin B1 Thiamine Effects: Conversion of carbohydrates into energy, essential for the functioning of the heart, muscles, and nervous system. Signs include incoordination, weakness, seizures and nerve damage.
Brain damage can occur from severe deficiency. Typically caused by a diet of raw fish which contains thiaminase. Sensitive to heat, alkali, oxygen and radiation and considerable amounts of the vitamin can be lost during cooking.
Wheat germ, rice and other whole grains, lean meats especially porkliver, fish, yeast, dried beans, peas, and soybeans. Vitamin B2 Riboflavin Effects: Plays a role in many enzyme reactions of the metabolism. Also important for growth, red blood cell production, maintenance of skin and coat, breakdown of protein, fat and carbohydrates.
Signs include decreased reproductive performance, dry skin, weakness, and anemia. Sensitive to light but heat stable. Lean meats, liver, fish, eggs, yeast, cheese, legumes, nuts, green leafy vegetables. Vitamin B3 Niacin Effects: Assists in the functioning of the digestive system, skin, and nerves and is also important for the conversion of food to energy.
The amino acid tryptophan is a provitamin of niacin. Signs include loss of appetite, bad breath, increased salivation, diarrhea and emaciation. Large doses of niacin can cause liver damage, peptic ulcers, and skin rashes.
Stable to light, heat, air and alkali. Liver, lean meat, poultry, fish, nuts, yeast, legumes, asparagus, seeds, green leafy vegetables. Vitamin B5 Pantothenic Acid Effects: Important in many enzyme reactions in metabolism and the synthesis of hormones.